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Educational Programs

2018 Annual Oration

Friday, November 30, 2018
2:00 pm – 3:00 pm  

The Beneficial Effects of the 100-year-old BCG Vaccine in Type 1 Diabetes

BCG is a live attenuated bacterial vaccine that contains the avirulent tuberculosis strain Mycobacterium bovis.  BCG has historically been given to protect against tuberculosis and, since its introduction in 1921, has been the most widely administered vaccine in the history of medicine.  BCG is considered to be extremely safe and roughly 100 million children per year globally receive the vaccine. BCG is also one of the most affordable medicines, costing less than a dollar a dose in many parts of the world.

Expanded use of BCG is occurring globally for the treatment of diverse human autoimmune diseases, allergies and to alter immunity to infections. The MGH based and ongoing clinical trials, centered mostly on type 1 diabetes, have recently shown that limited BCG dosing even in long term type 1 diabetics can restore blood sugars to the near normal range with over 8 years of clinical trial monitoring. These restored blood sugars in the normal range are not associated with hypoglycemia, a differentiator from insulin therapy and many additional clinical trials are underway.

The re-use of this affordable and safe drug to clinically regulate type 1 diabetic subject blood sugars is a lesson in the power of generic drug development for affordable and improved care. With new and existing federal legislation on the rights of patients for Expanded Access to generic drugs it is important for the medical community to be aware of these Boston based and global efforts as well to implement these possible transformative and affordable health care solutions.  

History of the Oration

The MMS Annual Oration dates back to 1804 when Dr. Isaac Rand delivered his dissertation entitled, On Phthisis Pulmonalis, and the Use of the Warm Bath.  For more than 200 years, MMS orators have addressed a wide spectrum of topics germane to the evolving practice of medicine.


About the Orator:

Denise Faustman, MD, PhDDenise Faustman, MD, PhD

Director of the Immunobiology Laboratory at the Massachusetts General Hospital (MGH) and an Associate Professor of Medicine at Harvard Medical School.

(Read full bio here)




Target Audience:  

Physicians, nurses, other healthcare professionals, and medical educators who are interested in learning more about the diagnosis and treatment of Type 1 Diabetes.

Activity Objectives

  • Discuss how repeat BCG vaccines can help restore immune balance in autoimmune disorders, such as type 1 diabetes, by inducing an increase in Treg suppressor T-cells and by killing cytotoxic T-cells.
  • Describe the beneficial effects of repeat BCG vaccination on glycemic control in type 1 diabetes, even in patients with advanced disease of greater than 20 years of duration, through induction of accelerated and regulated glucose uptake with aerobic glycolysis.
  • Summarize the rationale for re-introduction of the BCG vaccine for prevention of allergies and autoimmune disorders such as type 1 diabetes.  



Ethics Forum

Health Care as a Basic Human Right

November 30, 2018 
3:30-6:30

Forum Description:

Presented by the Massachusetts Medical Society’s Officers and the Committee on Ethics, Grievances, and Professional Standards, the Ethics Forum alerts physicians to the ethical implications of issues that arise in the practice of medicine and offers information on issues at the intersection of ethics, medicine, and professionalism. This year’s Ethics Forum will explore domestic and international attitudes on health care as a basic human right, focusing on the implications of recognizing health care as a human right for the US health care system.

Learning Objectives:

  • Define basic human rights 
  • Contrast the concept of health care as a right vs. privilege
  • Discuss international and domestic perceptions of health care as a human right
  • Describe the implications of recognizing health care as a human right in the United States


Speakers:


Accreditation Statement

The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement:  
The Massachusetts Medical Society designates each live activity for the number of AMA PRA Category 1 Credits™ listed below. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 2018 Annual Oration (The Beneficial Effects of the 100-year-old BCG Vaccine in Type 1 Diabetes): 1.00 AMA PRA Category 1 Credit TM
  • Ethics Forum (Health Care as a Basic Human Right): 3.00 AMA PRA Category 1 Credits TM

The above activities meet the criteria of the Massachusetts Board of Registration in Medicine for risk management study.

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Save the Date for These Upcoming Meetings

  • 2019 Annual Meeting- May 2-4, 2019 at the Seaport Hotel and World Trade Center, Boston 
  • 2019 Interim Meeting- December 6-7, 2019 at MMS Headquarters and the Westin Hotel, Waltham

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