Massachusetts Medical Society: What everyone should know…

What everyone should know…

About opioids…

Opioids act on the nervous system to relieve pain and work by reducing the number of pain signals that are sent to the brain. They are usually used to treat moderate to severe pain, and are commonly used during and after some surgical procedures. These drugs are all opioids: opium, codeine, fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, paregoric, sufentanil, vicodan, lortab, Percocet, Darvon, dilaudid, tramadol, and heroin, which is an “illegal” opioid, to name a few.  Some of these opioids can actually be used to treat opioid addiction.  Opioids are depressants, which means they slow down the central nervous system, causing drowsiness, a slow heart rate and breathing. Not everyone feels or responds to opioids in the same way. Opioids can be especially dangerous when used with other drugs, especially some allergy, sleep and anti-anxiety medications, and or alcohol. 

All opioids have the potential to be addictive and the longer opioids are used the risk for physical dependence and or addiction increases

About pain management…

The opioid epidemic has brought much needed attention to chronic pain and how best to treat it. Unfortunately there are no simple answers, and for many people finding appropriate treatment can be difficult. What has been learned about chronic non- cancer pain is that there are many effective non-opioid forms of treatment. Some of these options include physical therapy, massage, and acupuncture to name a few. Working with your physician to find the best treatment plan for you is important. Restoring function is the goal of pain management. 

About the opioid epidemic…

The current drug overdose epidemic is caused by the misuse of both prescription and non-prescription opioids. The epidemic of drug overdoses is primarily caused by fentanyl, which is an extremely potent synthetic opioid. The fentanyl that is found on the streets is illicitly manufactured. Frequently illicit or “street drugs” are purposely cut with other drugs to make them more powerful. Some drug overdoses are from combining opioids with other drugs that can intensify the effects of the opioids.

About physical dependence, tolerance and addiction…

Physical dependence can happen with the chronic use of some drugs—including many prescription drugs, even if taken as instructed. Physical dependence does not constitute addiction, but it often accompanies addiction. This difference can be difficult to discern, particularly with prescribed pain medications, for which the need for increasing dosages can represent tolerance or a worsening underlying problem, as opposed to the beginning of abuse or addiction.

Drug tolerance means that a person’s reaction to a drug decreases as they continue to use it. A person with a drug tolerance has to take larger doses in order to achieve the same effect as they did earlier in their drug use. Drug tolerance is not addiction. It is simply the body becoming desensitized to the drug’s effects.

Addiction is a chronic relapsing disease that effects the brain and behavior. Initially one has control over the use of a drug, but over time develops a powerful compulsion to use the drug. The ability to control impulses despite negative consequences is a hallmark of addiction.

People with an addiction tend to show the three Cs: craving for the object of the addiction, which can be mild to intense, loss of control over use of the object of the addiction, continued engagement with the object of the addiction in spite of harmful consequences.

There is no single factor that can predict who will develop an addiction. Genetic, environmental and developmental factors all influence the risk of developing an addiction. Many people have wrongly believed that people who have a drug addiction lack willpower or substance misuse is some kind of moral failing. Addiction knows no socioeconomic or ethnic boundaries. Addictions develop for a variety reasons that are unique to each individual. It is important to know that drug addiction can be treated and managed, but getting treatment and support can help make recovery possible. Addiction to opioids is called  “opioid use disorder” (OUD).

   

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