135th Annual Shattuck Lecture - GLP-1: Discovery and Impact on Health
Glucagon-like peptide-1 (GLP-1) has emerged as a key regulator in metabolic health, with profound implications for diabetes management, weight loss, and cardiovascular protection. The 135th Annual Shattuck Lecture explores the discovery, physiological
role, and therapeutic applications of GLP-1 receptor agonists (GLP-1 RAs). Participants will gain insight into the patient selection criteria, the broader impact of GLP-1 modulation, and potential future applications of GLP-1-based therapies.
Faculty
Moderator
Eric J. Rubin, MD, PhD
Editor-In-Chief, The New England Journal of Medicine, NEJM Group
Shattuck Lecturer
Joel F. Habener, MD
Professor of Medicine (Emeritus), Harvard Medical School
Honorary Scientist, Massachusetts General Hospital
Former Investigator, Howard Hughes Medical Institute
Discussion With Editors
Julie R. Ingelfinger, MD
Deputy Editor, The New England Journal of Medicine
Professor of Pediatrics, Harvard Medical School
Senior Consultant, Pediatric Nephrology, Mass General for Children at MGB
Clifford Rosen, MD
Associate Editor, The New England Journal of Medicine
Professor of Medicine, Tufts University School of Medicine
Senior Scientist, MaineHealth Institute for Research
Intended Audience
This activity is designed for physicians, physicians-in-training, other health care leaders and professionals and students.
Course Objectives
Upon completion of this activity, learners should be able to:
- Discuss the history and discovery of GLP-1 and its relevance to metabolic health
- Explain the physiologic role of GLP-1 in health and disease
- Define patient selection criteria and considerations for prescribing GLP-1 receptor agonists
- Evaluate the public health impact of GLP-1 based interventions on disease management and health care outcomes
- Describe ongoing research that could expand the role of GLP-1 therapies
Accreditation & Credit Information
Accreditation Statement
The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
AMA Credit Designation Statement
The Massachusetts Medical Society designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation
in the activity.
ABMS MOC Approval Statement
Through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, This activity has met the requirements as a Lifelong Learning CME Activity (apply toward general CME requirement) for the following ABMS Member Boards:
Allergy and Immunology
Anesthesiology
Colon and Rectal Surgery
Family Medicine
Medical Genetics and Genomics
Nuclear Medicine
Ophthalmology
Physical Medicine and Rehabilitation
Plastic Surgery
Preventive Medicine
Psychiatry and Neurology
Radiology
Urology
National Commission on Certification of Physicians Assistant (NCCPA)
Physician Assistants may claim a maximum of 1.00 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited
by ACCME or a recognized state medical society.
Exam/Assessment: A score of 70% or higher is required to receive AMA PRA Category 1 Credit(s)™.
Course Fees:
Massachusetts Medical Society (MMS) Physician Member: $40.00
MMS Resident/Student Member: FREE
Non-Member Physician: $90.00
Non-Members Resident/Student: $20.00
Allied Health Professional/Other: $32.00
Activity Term:
Original Release Date: June 18, 2025
Review Date(s): N/A
Termination Date: June 18, 2028
Format and Estimated Time to Complete: Video & Resources/1 hour
System Requirements
Desktops/Laptops
Windows 10
Mac OSX 10.6 higher
Most modern browsers including
IE 11+
Firefox 18.0+
Chrome latest version
Safari 12+
Mobile/Tablet
iOS devices beginning with OS version 10 or higher (includes, iPhone, iPad and iTouch devices)
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Contact us at nejmcust@mms.org or (800) 843-6356. Massachusetts Medical Society, 860 Winter Street, Waltham, MA 02451.
