Evidence-based Medication Management of Early Pregnancy Loss
Course Overview
Approximately 80% of all cases of pregnancy loss occur within the first trimester, and more than 1 million people in the US annually experience early pregnancy loss (EPL). This activity presents the most up-to-date
scientific evidence, detailed steps for medical management of EPL, and REMS (Risk Evaluation & Mitigation Strategy) protocols for mifepristone administration. At the end of this evidence-based review and patient case, you'll be equipped with the
knowledge and skills to offer EPL medical management in most clinical scenarios.
Faculty

Rebekah Rollston, MD, MPH
Family Medicine Physician, Cambridge Health Alliance Instructor in Medicine, Harvard Medical School, Faculty Affiliate, Harvard Medical School Center for Primary Care
Dr. Rollston is a Family Medicine
Physician at Cambridge Health Alliance, Instructor in Medicine at Harvard Medical School, Affiliate Editor-in-Chief of the Harvard Primary Care Blog, and Founder & Executive Director of Doctors For A Healthy US, LLC. She earned her Medical Degree
from East Tennessee State University Quillen College of Medicine and her Master of Public Health (MPH) from The George Washington University Milken Institute School of Public Health. Her professional interests focus on social determinants of health
& health equity, gender-based violence, sexual & reproductive health, addiction medicine, rural health, homelessness & supportive housing, and immigrant health. She has published on these topics in The Lancet, American Journal of Health Promotion,
and Medical Care. And further, Dr. Rollston is currently a Visiting Scholar in the Northeastern University Women, Gender, and Sexuality Studies Program (AY 2020-2021), where she’s studying the intersection of COVID-19, population health outcomes,
and women’s leadership styles internationally. Dr. Rollston is an active member of the Harvard Joint Committee on the Status of Women, Massachusetts Medical Society Committee on Public Health, and also an External Affiliate of the RTI Global Gender
Center.

Lauren Sobel, DO, MPH
Complex Family Planning Fellow, Department of Obstetrics & Gynecology, Brigham & Women’s Hospital/ Harvard Medical School
Dr. Sobel earned her doctor of osteopathy (DO) degree and Masters in Public Health (MPH) at Touro University in Vallejo, California. She then moved to Boston where she completed her Obstetrics & Gynecology residency at Boston Medical Center. She is currently
a Complex Family Planning fellow at Brigham and Women's Hospital/Harvard Medical School. Her professional interests focus on the labor and delivery and contraception experience of women with opioid use disorder and the intersection of intimate partner
violence and trauma-informed abortion care.
Intended Audience
The target audience for this educational activity is primary care, emergency, and OB/GYN providers, as well as any other health professionals providing reproductive
healthcare..
Course Objectives
- Define Early Pregnancy Loss (EPL)
- Review evidence-based EPL diagnostic criteria
- Compare evidence-based EPL medical management regimens
- Identify evidence-based EPL follow-up options
Course Fees
Massachusetts Medical Society (MMS) Physician Member: $20.00
MMS Resident/Student Member: Free
Non-Member Physician: $45.00
Non-Members Resident/Student: $10.00
Allied Health Professional/Other: $16.00
Format & Estimated Time to Complete: Video, 1 hour
Accreditation Statement
Accreditation and Credit Information
The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education
for physicians.
AMA Credit Designation Statement
The Massachusetts Medical Society designates this internet enduring material for a maximum of 1.00 AMA PRA Category 1
Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity meets the criteria for the Massachusetts Board of Registration in Medicine for risk management study.
MOC Approval Statement
Through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, this activity has met the requirements as a MOC Part II CME Activity (apply toward general CME requirement) for the following ABMS Member Boards:
Family Medicine
National Commission on Certification of Physicians Assistant
(NCCPA)
Physician Assistants may claim a maximum of 1.00 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credits™ from organizations accredited by ACCME or a recognized state medical society.
Exam/Assessment: A score of 70% or higher is required to receive AMA PRA Category 1 Credits™.
Activity Term
Original Release Date: January 8, 2020
Review Date (s): N/A
Termination Date: January 8, 2023
Course Developers, Reviewers & Web Producer:
Kari P. Braaten, MD, MPH, Medical Director, Fish Center for Women’s Health, Brigham and Women’s Hospital; Associate Fellowship Director, Fellowship in Complex Family Planning; Assistant
Professor of Obstetrics, Gynecology and Reproductive Medicine, Harvard Medical School
Alexandra Spadola, MD, Medical Director, Labor & Delivery, Visiting Associate Professor, Department of Obstetrics & Gynecology, Tufts Medical Center & Tufts
University School of Medicine
Danna G. Muir, MBA, Director, Accreditation & Recognition, NEJM Group Education
Jane E. Gagne, Manager, Accreditation and Education Compliance, NEJM Group Education
Sara G. Shields, MD, MS, FAAFP, Family
Medicine with Obstetrics, UMass Memorial Health Care and Professor, University of Massachusetts Medical School
Thelma J. Tatten, Web Content Production Specialist, NEJM Group Education
System Requirements
Desktops/Laptops
Windows, XP, Vista, 7, 8
Mac OSX 10.6 higher
Most modern browsers including:
IE8,9,10
Firefox 18.0+
Chrome 26+
Safari 5+
Flash player is required for some Online CME courses.
Mobile/Tablet
iOS devices beginning with OS version 5 or higher (includes, iPhone, ipad and iTouch devices)
Android devices including tablets and phones.
Windows RT and tablets on Windows 8 are also supported.