Question 4

5/28/2013

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Question 4

5/28/2013

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Atrial fibrillation (AF)

5/24/2013

, such as the CHADS2 score, can help identify which AF patients are at high risk of stroke. Generally … for thrombo embolism prophylaxis in such high-risk patients,and can reduce the risk of stroke by an impressive … two-thirds.41 In intermediate risk patients, those with CHADS2 score of 1, aspirin or anticoagulants can …

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References

5/24/2013

for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ. January 12, 20022002;324 … Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial … Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf …

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Elective PCI

5/24/2013

% relative reduction in the combined risk of death, MI, or stroke (absolute reduction of 3%; p=0.02) compared … receiving a, clopidogrel 75 mg daily should be given for at least 12 months if patients are not at high risk … and ideally up to 12 months (unless the patient is at increased risk of bleeding; then it should be given …

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Stroke

5/24/2013

for the acute management of ischemic stroke has been evaluated in trials including over 40,000 patients, which … reduced the risk of recurrent stroke (relative risk reduction 23.1%; p=0.006) but had a smaller impact … on the composite end-point of stroke or death risk reduction 12.9%; p=0.056). The European/Australasian Stroke …

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Recent or remote MI

5/23/2013

for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial … MI, aspirin reduces the risk of subsequent vascular events by more than 25%.8 The CAPRIE trial …, but the magnitude of this advantage was small (0.5% absolute reduction in risk, 8.7% relative reduction in risk …

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Acute coronary syndromes

5/23/2013

management of MI has been evaluated in 15 trials including about 19,000 patients.3 , 4 , 7 Together … for an average of one month reduces the risk of re-infarction, stroke or cardiovascular death by 30%.8 Aspirin … also reduces the risk of a major vascular event by 46% when given acutely to patients with unstable …

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Introduction

5/23/2013

in Patients at Risk of Ischemic Events (CAPRIE) trial in 1996. Several large randomized trials have evaluated … application of these studies can be challenging, because while dual antiplatelet therapy reduces the risk … of cardiovascular events, it also increases the risk of bleeding. The same trade-off also applies to newer products …

/Templates/CME/Chapter.aspx?id=4294970157

Medical Marijuana: DPH Memo to Public Health Council (pdf)

3/29/2013

of the medical use of marijuana outweigh any associated health risks for the patient. The law allows … substance abuse treatment, pain management), including the Massachusetts Chapter of the American Academy … the potential benefits and risks of marijuana use, and has a role in the ongoing care and treatment …

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